About NanoForge

Our Mission

NanoForge was created to democratize nanoparticle design and accelerate nanomedicine research. By providing a scientifically accurate yet accessible platform, we aim to:

• Enable researchers to design stable nanoparticles with predictable properties
• Support educational initiatives in nanoscience and nanotechnology
• Foster collaboration and innovation in nanomedicine development
• Provide a reliable tool for evaluating physical constraints in nanoparticle design

We believe that better tools lead to better science, and ultimately to improved nanomedicine solutions for global health challenges.

The Science

NanoForge combines principles from colloidal science, biophysics, and materials science to provide accurate modeling of nanoparticle behavior. Our calculations incorporate:

• Sequence-Based Thickness: DNA/RNA layer thickness calculated from actual nucleotide sequences (0.34nm per nucleotide)
• Steric Hindrance Effects: Realistic modeling of molecular crowding on nanoparticle surfaces
• Physical Packing Limitations: Accurate calculation of maximum surface coverage based on molecular footprints
• Temperature-Dependent Aggregation: Modeling of thermal effects on colloidal stability
• Environment-Specific Behavior: Accounting for pH, ionic strength, and medium composition

All calculations are based on peer-reviewed scientific literature and fundamental physical principles in nanoscience.

Technology

NanoForge is built using modern web technologies to ensure accessibility, performance, and scientific accuracy:

• Front-End: HTML5, CSS3, and vanilla JavaScript for maximum compatibility
• Visualization: Three.js for real-time 3D rendering of nanoparticle structures
• Scientific Computing: Custom algorithms for physical property calculations
• Export Capabilities: PDF and data export functionality for research documentation

The application runs entirely client-side, ensuring your design data remains private and secure.

Team